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Lab People

Dale Frank - Principal Investigator
Professor
Department of Biochemistry - Rappaport Faculty of Medicine
Technion - Israel Institute of Technology
Lab: 04-829-5286 (International: 972-4-829-5286)
dale@technion.ac.il

 

 

I did my Ph.D. at Hebrew University - Hadassah Medical School, under the joint mentorships of Professors Howard Cedar and Aharon Razin. I studied the "wonderful" nature of how DNA methylation patterns are established in embryonic cells. Next, I spent 3-years at the University of California, Berkeley, in the lab of Professor Richard Harland, learning the "enchanted" world of Xenopus laevis development.  My lab at the Technion enthusiastically exploits the accessible Xenopus system to investigate the earliest events regulating nervous system cell fate formation in vertebrate embryos. We leverage the vertebrate frog embryo as a "simplified" system to recapitulate and understand the etiology of genetic disease caused by the disruption of early human nervous system development.

Lab Members

 
Hava Lichtig, Ph.D., Tel Aviv University, 2012
Lab Manager
Research Interests: Utilizing Xenopus as an embryonic model system platform to understand human nervous system genetic disease etiology (Bainbridge Ropers Syndrome). 
 
Hanna Polevoy, Ph.D. student
Research Interests: Regulation and evolutionary conservation of neural crest formation by homeodomain proteins.
 
Pavel Federenchik, M.D./Ph.D. student
Research Interests: Meis protein as a paradigm to study evolution of neural inducing functions in metazoans.​
Chen Itzkovich, Ph.D. student
Research Interests: Utilizing Xenopus as an embryonic model system platform to understand human nervous system genetic disease etiology (Sifrim-Hitz-Weiss Syndrome).
 
 
 
 
 
 
 
 
Lab Reunion - Sara's Retirement Party
April 2013
Past and Present Members

 

 
 
 
 

 

 

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